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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC18 All Species: 17.88
Human Site: S44 Identified Species: 35.76
UniProt: Q5T9S5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T9S5 NP_996769.2 1454 168962 S44 Q S L G E E L S S V S P S E N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537071 1456 169626 S44 Q S L G E E L S S V S P S E N
Cat Felis silvestris
Mouse Mus musculus Q640L5 1455 169723 S46 H N L G E E L S S V S P S E N
Rat Rattus norvegicus XP_001060717 1462 170487 S45 H N L G E E L S S V S P S D Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508531 925 106760
Chicken Gallus gallus XP_001232490 1295 151316 T44 A E L S S T G T R E H S D R C
Frog Xenopus laevis Q9PW73 1335 154049 H45 K R D H S S E H S L S R V P L
Zebra Danio Brachydanio rerio XP_692712 779 89837
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P02566 1966 225108 S90 F E K T E D M S N L S F L N D
Sea Urchin Strong. purpuratus XP_796315 2152 245292 L66 P A L T L D D L T P D R L A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LW85 726 81954
Baker's Yeast Sacchar. cerevisiae P25386 1790 206434 S188 I S L P T S I S T M V S L L D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 90.1 N.A. 84.4 83.5 N.A. 41.4 49.3 39.8 22.7 N.A. N.A. N.A. 20.2 22.9
Protein Similarity: 100 N.A. N.A. 95.4 N.A. 92.4 91.4 N.A. 51 65.2 59.5 37.2 N.A. N.A. N.A. 40 40
P-Site Identity: 100 N.A. N.A. 100 N.A. 86.6 73.3 N.A. 0 6.6 13.3 0 N.A. N.A. N.A. 20 6.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 93.3 86.6 N.A. 0 13.3 26.6 0 N.A. N.A. N.A. 53.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 22.4 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. 35.7 40.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 9 0 0 17 9 0 0 0 9 0 9 9 17 % D
% Glu: 0 17 0 0 42 34 9 0 0 9 0 0 0 25 0 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 0 0 34 0 0 9 0 0 0 0 0 0 0 0 % G
% His: 17 0 0 9 0 0 0 9 0 0 9 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 59 0 9 0 34 9 0 17 0 0 25 9 9 % L
% Met: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % M
% Asn: 0 17 0 0 0 0 0 0 9 0 0 0 0 9 25 % N
% Pro: 9 0 0 9 0 0 0 0 0 9 0 34 0 9 0 % P
% Gln: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 0 0 0 0 0 9 0 0 17 0 9 0 % R
% Ser: 0 25 0 9 17 17 0 50 42 0 50 17 34 0 9 % S
% Thr: 0 0 0 17 9 9 0 9 17 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 34 9 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _